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KMID : 0043320050280111239
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Archives of Pharmacal Research
2005 Volume.28 No. 11 p.1239 ~ p.1243
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Norditerpenoid Alkaloids and Other Components from the Processed Tubers of Aconitum carmichaeli
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Shim Sang-Hee
Lee So-Young
Kim Ju-Sun
Son Kun-Ho
Kang Sam-Sik
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Abstract
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A new norditerpenoid and a known alkaloid were isolated from the alkaloidal fraction of the processed tubers of Aconitum carmichaeli. The structure of the new norditerpenoid alkaloid was elucidated as lipoforesaconitine (1) on the basis of spectroscopic analysis. The known norditerpenoid alkaloid was characterized as lipoyunanaconitine (2). In addition, a new flavonoid, 6’-O-acetylliquiritin (7), along with a known ceramide, (2S,3S,4R,8E)-2-[(2’R)-2’hydroxylignoceroylamino]-8(E)-octadecene-1,3,4-triol (3), as well as a known steroid saponin, gracillin (8), and three known flavonoids, Iiquiritigenin (4), isoliquiritigenin (5), and liquiritin (6), were also isolated and characterized. All known compounds were isolated from this plant for the first time. The structures of the isolates were established by spectroscopic and chemical methods.
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KEYWORD
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Prepared aconite, Aconitum carmichaeli, Ranunculaceae, Norditerpenoid alkaloid, Flavonoid, Steroid saponin
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